Finding Exceptional Motifs in Sequences

The main question R'MES* addresses is "does this motif occur in that biological sequence with an expected frequency?" In other words, can we observe it so many times, or so few times, just by chance? Usually, when the answer is no, such "exceptional" motif is a candidate to have a particular biological meaning; only a candidate: statistical significance is not equivalent to biological significance.

This web site provides all you need to run R'MES on your own datasets: tutorials, source code, command line user guide and links to the web interface and to a graphical user interface to visualize R'MES results.

When using R'MES, please cite: Schbath, S. and Hoebeke, M. (2011). R'MES: a tool to find motifs with a significantly unexpected frequency in biological sequences. In Advances in genomic sequence analysis and pattern discovery (L. Elnitsk i, O. Piontkivska, and L. Welch, eds.). Science, Engineering, and Biology Informatics, vol. 7. World Scientific.

* Recherche de Mots Exceptionnels dans une Sequence